Mutaflor, 100 capsules

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Mutaflor – a probiotic with E. coli strain Nissle 1917. 100 enteric coated capsules.


One hard-capsule ­Mutaflor contains Escherichia coli strain Nissle 1917 as its active pharmaceutical ­ingredient (API), equivalent to 2.5–25 x 109 viable cells (CFU). These capsules possess an enteric coating. They only open in the terminal ileum or at the beginning of the colon where they release the active substance.

Suggested use

Adolescents and adults take 1 capsule ­Mutaflor daily from day 1 to 4, then 2 capsules daily. In case of persistent constipation, a daily intake of up to 4 capsules ­Mutaflor might be reasonable. The standard dose should be taken unchewed and with plenty of liquid during a meal, preferably ­breakfast. 

Potentially occurring flatulence is invariably a sign of a too high dose application and will mostly disappear when the dose is reduced. The daily dose of several capsules must not be taken at one time, but may be distributed over the day and taken with regular meals.


The probiotic medicinal product ­Mutaflor contains ­viable bacteria in a high concentration. For this reason, it should be stored in a refrigerator at a temperature ranging between +2° C and +8° C. An interruption of chilling for a few days will have normally no influence on the number of viable cells. In case of prolonged heat exposure, however, the bacterial cells will to some extent lose their viability. No toxic substances will be developed.

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